AVIPure® - AAV9 10 mL settled resin
Category |
Description |
Target |
Adeno-associated virus (AAV9) vectors |
Base matrix |
Cross-linked agarose, spherical |
Particle size (d50v) |
~ 50 µm |
Residence time |
1-4 minutes
|
Binding capacity |
2E14-1E15 vp/mL of resin depending upon residence time, mutations and composition of feed stock
|
Buffer compatibility |
Stable to all commonly used aqueous buffers, including 8 M urea, 6 M guanidine hydrochloride, ethylene glycol, and detergents |
Solvent compatibility |
Water, alcohol (0-20% v/v), acetonitrile, 1-2M acetic acid, other common organic solvents |
pH stability |
1-13 |
Cleaning-in-place stability |
0.1-0.5 M NaOH |
Pressure/flow (min.) |
>300 cm/hr at 3 bar in a 2.6 x 20 cm column pressure packed at 4 bar |
Delivery conditions |
2% benzyl alcohol |
Storage |
2-8 °C, 2% benzyl alcohol; do not freeze |